Objective:To evaluate the clinical effect of ultrasonic dissector(CUSA) in hepatectomy and partial liver transplantation. Methods:The clinical data were retrospectively analyzed among group of CUSA and without CUSA method. Results:The intraoperative bleeding and postoperative drainage of the CUSA group were significantly less than the group of without CUSA method. The aminotransferase(ALT) of with CUSA group also is lower than without CUSA group. Conclusion:CUSA is a kind of safe and effective instrument in hepatectomy,which should be suggested to apply in clinic.