Investigation of prognosis relationship between anti-cardiolipin antibodies?D-Dimer and the patients with acute cerebral infarction
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    Abstract:

    Objective:To explore relationship between anti-cardiolipin antibodies(ACA)-D-Dimer and acute cerebral infarction. Methods:The content of ACA-D-Dimer in blood serum of 187 acute cerebral infarction patients was detected in the morning after fasting over night using ELISA methods, and compared with 135 average healthy cases. Results:The ACA positive rate in acute cerebral infarction group was much higher than control and the difference was statistically significant(P < 0.01); The content of D-Dimer in ACA-positive group was significantly higher than that in ACA-negative group; As the cerebral infarction worsenly, the IgG-ACA positive rate became higher as well as the content of D-Dimer; ACA in the 1st,2nd,3rd and 4th week were compared, suggesting that ACA positive rate reduced as time changed(P < 0.01); ACA positive status was closely related with cerebral infarction patients who were 50 years old or younger. Conclusion:The dynamic changes of ACA-D-Dimer in blood serum might be helpful in predicting prognosis of acute cerebral infarction.

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吴 晋.血清抗心磷脂抗体?D-二聚体与急性脑梗死关系的研究[J].南京医科大学学报(自然科学版英文版),2008,28(12):1595-1597.

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  • Received:July 13,2008
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