Objective:To evaluate the value of 64-slice CT coronary angiography(64SCTCA)in the diagnosis of coronary heart disease. Methods:With 64SCTCA, the images of 118 cases were analyzed retrospectively. Results:There were 116 of 118 cases showed the main branches of coronary arteries successfully by 64SCTCA examination. 77 cases of coronary artery lesions of various branches were found, including 61 cases totally 82 branches of coronary artery stenosis. There are 2 cases of coronary artery stent placement got the other coronary artery branches postoperative stenosis, 2 branches restenosed in 10 cases of coronary stent placement. 2 branches occluded in 3 cases of coronary artery bypass surgery. 5 cases of myocardial bridge were detected. 80 plaques were detected from 77 cases. Conclusion:64SCTCA showed coronary artery stenosis clearly and could be used to screen for coronary heart disease. It has unique advantage on evaluation of coronary plaque and postoperative situation, such as coronary stent placement and coronary artery bypass surgery. Furthermore, diagnosis of myocardial bridge by 64SCTCA was superior to coronary angiography.