Objective:To compare the stability and achievement ratio between two rat models of stress urinary incontinence(SUI),which are developed by simulated birth trauma and urolysis. Methods:Forty-five female virgin Sprague-Dawley rats were divided into 3 groups:five rats were selected randomly for the control group. and remaining rats were divided into group A and B randomly and equally. Rats of group A received vaginal injury operation and bilateral oophorectomy,while urolysis and bilateral oophorectomy was performed on rats of group B. After then,group A and B were divided into four subgroups,each subgroup contained 5 rats. Urodynamic parameters,LPP and ALPP,and histological examinations were carried out post-operation on Week 1,Month 1,Month 2 and Month 3. Results:Compared with reference value,both LPP and ALPP of group A and B decreased significantly(LPP:A1~A3 P < 0.01,A4 P < 0.05,B1~B4 P < 0.05;ALPP:A1~A3 P < 0.01,A4 P < 0.05,B1~B4 P < 0.01). There was no statistical difference between group A and B. In addition,there was no statistical difference among subgroups from A1 to A4(P > 0.05) in group A,and subgroups from B1 to B4(P > 0.05) in group B. Histological examinations showed atrophy and disruption of smooth muscle layers,as well as decreased innervation. Conclusion:Both of simulated birth trauma and urolysis can be successfully applied in developing rat model with satisfactory stability of 3 months after operation. Birth trauma model can be established with higher success rates,and has the advantage of low learning curve. Therefore,it can be widely used as the model of SUI.