Characterization of calreticulin in adult mouse testis
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    Abstract:

    Objective:To investigate expression and distribution of calreticulin (CRT) in the adult mouse testis and explore the preliminary function of CRT during testes development and spermatogenesis. Methods:The expression and distribution of calreticulin (CRT) in the adult mouse testis were detected by western blotting (WB) and Immunohistochemistry (IHC). Results:Western blotting result showed CRT expressed highly in mouse testis. Immunohistochemistry result revealed positive signals were widely distributed while strong signals were mainly in primary spermatogonia and Leydig cells. Conclusion:CRT expressed highly in adult mouse testis,and it may be involved in spermatogonia self-renew/differentiation and testosterone secretion mechanisms.

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卢秀真,吴亦波,周作民,黄晓燕.钙网蛋白calreticulin在小鼠睾丸中的表达及意义[J].南京医科大学学报(自然科学版英文版),2010,(9):1219-1222.

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  • Received:May 09,2010
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