Objective:To provide basis for the early diagnosis and prevention of coronary atherosclerotic heart disease (CHD) by calculating the ratio of pulse pressure (PP)/ankle-brachial index(ABI). Methods:Total 120 cases of hypertension patients were randomly selected. They were divided into two groups according to coronary angiography(CAG)and clinical manifestation,group A:CHD group,group B:non-CHD group. The average of 24-hour systolic blood pressure(SBP),diastolic blood pressure(DBP),PP,PP/ABI and some other risk factors of CHD between the two groups were compared;the predictive value of CHD was judged by Logistics regression analysis with the above factors,and the ratio of PP/ABI was analyzed;the cutoff value,specificity,sensitivity,positive predictive value and negative predictive value of in diagnosing CHD were predicted with the method of receiver operator characteristic(ROC) analysis. Results:There were no significant differences in SBP,DBP,PP and ABI between the two groups,but there existed great differences in total cholesterol,low density lipoprotein,diabetes and so on. PP and ABI correlate with PP/ABI. The ratio of PP/ABI differed between the two groups,which had statistical significance(P=0.001). Correlation and regression analysis indicated that there was independent predictive value of the PP/ABI ratio in the diagnosis of CHD. ROC analysis indicated that when the cut point equalled to or above 55.9,the sensitivity of predicting hypertensive patients with CHD is 65.9%,the specificity is 32.9%,the positive predictive value is 53.7% and the negative predictive value is 77.3%. Conclusion:In the diagnosis of hypertension patients with CHD,the ratio of PP/ABI is more sensitive than ABI or PP. The ratio of PP/ABI has clinical value in the early identification of hypertension patients with CHD.