Analysis on the clinical features of the patients with type 2 diabetes and primary hypertension
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    Abstract:

    Objective: To observe average blood sugar,lipid profiles,serum uric acid level,cardio-cerebrovascular diseases and urinary albumin excretion incidence in type 2 diabetic patients with or without hypertension. Methods:Seven hundred and fifty five patients with type 2 diabetes were recruited and divided into normal blood pressure group(n=428)and hypertension group(n=324). Age,body mass index(BMI),HbA1c,total cholesterol(TC),triglyceride(TG),HDL-C,LDL-C,serum uric acid(SUA),urinary albumin excretion(UAE)rate were detected,the incidence of cardiovascular and cerebrovascular diseases were calculated. Results:Subjects with type 2 diabetes and primary hypertension accounted for 43.1% in this study population;age,gender,HbA1c and duration of diabetes in hypertension group were not different to those in normal blood pressure group(P > 0.05). BMI[(24.9±3.7) kg/m2],TC[(4.9±1.3) mmol/L],LDL-C[(3.1±1.2) mmol/L],TG[(2.5±3.0) mmol/L],SUA[(325.2±122.9) μmol/L] in hypertension group were higher than those in normal blood pressure group. The UAE rate[(47.7±91.4) mg/g] and positive ratio of UAE(24.3%),the cardiovascular and cerebrovascular diseases rate(15.1%)in hypertension group were higher significantly(P < 0.05,P < 0.01,respectively). Conclusion:Patients with type 2 diabetes mellitus and hypertension are prone to suffer from dyslipidemia,hyperuricemia,cadio-celebrovascular diseases and nephropathy than patients without hypertension.More attention should be paid to improve blood glucose,lipid profiles,uric acid and blood pressure control and prevent diabetic cardia-cerebrovascular and renal complications.

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唐 伟,李剑波,段 宇,刘 超,杨 涛.2型糖尿病合并原发性高血压患者临床特征分析[J].南京医科大学学报(自然科学版英文版),2010,(11):1633-1635.

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  • Received:April 16,2010
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