Development and linear growth in diabetic children who receiving insulin pigment
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    Abstract:

    Objective:To ascertain if there is difference between the development and linear growth of children diagnosed with diabetes who have been receiving insulin pigment and unaffected children. Methods:Retrospective analysis of 57 children with diabetes who were diagnosed from the ages of 6 to 10 years old(26 boys and 31 girls),record their height and weight until they reached their 18th birthday. Results:At the onset of diabetes,diabetic children were slightly taller than unaffected children. When they reached their finial height,they were slightly shorter than unaffectd people,however,there was no significant difference between the two groups both in these two periods. The onset of puberty was delayed significantly both in boys and girls. The median age of onset of puberty was 12.62(95%CI 11.54~12.50) years in diabetic boys versus 10.55(10.27~10.79) years in general-population boys and 11.13(95%CI 10.8~11.46) years versus 9.2(9.06~9.32) years in girls,with the menarche of diabetic girls starting at 14.15(13.64~14.65) years versus 12.27(12.16~12.39) years. All the children with diabetes were thinner than the general-population children when they were diagnosed [male BMI:(14.45 ± 1.35) kg/m2 versus(16.08 ± 0.59) kg/m2,t = -0.63,P < 0.05;female BMI:(13.50 ± 1.87) kg/m2 versus(15.46 ± 0.45) kg/m2,t = -6.67,P < 0.05],however,as they reached their finial height,they became fatter,especially the females[male BMI(21.43±1.62)kg/m2 versus(20.80 ± 0.00) kg/m2,t = 1.97,P > 0.05;female BMI(23.95 ± 2.37) kg/m2 versus(20.30 ± 0.00) kg/m2,t = 8.60,P < 0.05]. Conclusion:The development of patients with diabetes who have been receiving insulin pigment were still adversely affected but the finial height haven’t been affected significantly. All the children,especially girls,became fatter when they reached their finial height.

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毛 莉,陆卫平,季 峰,吕述军.强化胰岛素治疗后1型糖尿病儿童生长发育情况调查[J].南京医科大学学报(自然科学版英文版),2011,(8):1208-1211.

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  • Received:March 17,2011
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