Abstract:Objective:To analyze the effect of abnormal glucose metabolism on left ventricular function of senile patients with coronary heart disease through echocardiogram. Methods:Total 87 cases of patients with coronary heart disease but without myocardial infarction were definitely diagnosed by coronary angiography. According to the diagnosis and classification criteria,all of the patients were divided into the following three groups:diabetes mellitus(DM) group,impaired glucose tolerance(IGR) group and normal glucose metabolism group. Left ventricular eject faction(LVEF) and left atrium volume index(LAVI) were assessed by two dimensional echocardiography. The mitral valve and aortic valve blood flow spectra were obtained through pulse Doppler. Vp of early flow into the left ventricular cavity in normal and hypertensive patients were measured by color M-mode Doppler echocardiography. The mitral flow velocity was measured and the E/A was calculated. The mitral annular early diastolic velocities(Em) were determined by DTI(Doppler tissue imaging),and the E/Em and Tei index were calculated. Then the function parameters of the three groups were compared with the control. Results:Compared with normal glucose metabolism group,the patients from DM group and IGR group had higher left ventricular Tei index,E/Em,and LAVI,lower Vp,and the differences between them were significant. What’s more,the above four parameters correlated well. Conclusion:To patients with coronary heart disease simultaneously without myocardial infarction,LAVI,E/Em,Vp and left ventral Tei index could reflect the influence of glucose metabolism disorders on left ventral function earlier than index of EF and E/A.