Objective: To explore the effects of the laryngeal mask airway (LMA) and the traditional endotracheal intubation (TT) in general anesthesia children with congenital heart disease. Methods: Sirty children (ASA Ⅰ~Ⅱ) with congenital heart disorders,were randomly divided into two groups:laryngeal mask airway group (LMA group,30 cases) and endotracheal intubation group (TT group,30 cases). LMA was inserted following the intravenous infusion of propofol (1.5 mg/kg) and remifentanil (2 μg/kg) in LMA group,while in TT group endotracheal intubation was set up following the intravenous administration of propofol (1.5 mg/kg),remifentanil (2 μg/kg) and rocuronium (0.6 mg/kg). Anesthesia was maintained with propofol and remifentanil micro pump infusion,intermittent intravenous rocuronium. The length of time for operation and recovery from anaesthesia in two groups were recorded,and the values of MAP,HR,SpO2 at different time points(before anaesthesia induction,before insection of LMA or TT,immediately after insection of LMA or TT,before and after the removal of LMA or TT) were observed. Meanwhile,the successful rate of first placement was compared in two groups. Results: There were no significant differences between the two groups in the length of time for operation and recovery from anaesthesia(P > 0.05),as well as the values of MAP,HR,SpO2 before induction,before insection and before remove of LMA or TT(P > 0.05). However,the values of MAP,HR,SpO2 were significantly higher in TT group than those in LMA group immediately after insection and after removal of LMA or TT (P < 0.05). The incidence of postoperative respiratory complications in LMA group was significantly lower than that in TT group. Conclusion: Application of laryngeal mask airway for general anesthesia in the interventional therapy of children with congenital heart disease could not only achieve an effect of hemodynamic-stabilization,but also reduce postoperative respiratory complications because of its less stress response.