Objective:To analyze the efficacy of comprehensive therapy mainly using hysteroscopic adhesiolysis by mini-scissors. Methods:In a retrospective study,122 patients were received hysteroscopic adhesiolysis,which was carried out by mini-scissors,and monitored by ultrasonography. After operation,they received intrauterine devices(IUD) placement,with a following cycling hormonal therapy. After 3 months therapy uterine cavity and menstrual flow were evaluated. Results:Menstrual flow was normal in 68.0% of patients and uterine cavity returned to be normal in 109 patients,accounting for 89.3%. Re-operation was needed in 13 patients because of mild or moderate adhesion. Pregnant rate was 52.8% during the first year. Conclusion:The comprehensive therapy for intrauterine adhesion has good effect and deserves to be recommended in clinic.