Chronic kidney disease and associated cardiovascular risk factors in type 2 diabetes
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    Abstract:

    Objective:To determine the frequency of chronic kidney disease(CKD) and it’s associated cardiovascular risk factors in type 2 diabetic patients. Methods:A cross-sectional study was conducted in Jiangsu Province Official Hospital from January 2008 to December 2009. eGFR was calculated using the Modification of Diet in Renal Disease(MDRD) study equation. CKD was defined as the presence of albuminuria or eGFR < 60 ml/(min·1.73 m2). Albuminuria was defined as urinary albumin-to-creatinine ratio(ACR)≥30 mg/g. Risk factors associated with CKD were evaluated using logistic regression. Results:In total,1 521 outpatients with type 2 diabetes mellitus[(mean age (63.9 ± 12.0)years] were recruited. The frequency of CKD and albuminuria was 31.0% and 28.9% in the study cohort,respectively. After adjusted by sex and age,hypertension,duration of diabetes and anemia were significantly associated with CKD with odds ratio of 1.932(95% CI:1.275~2.929,P = 0.002),1.029(95% CI:1.001~1.058,P = 0.040) and 1.696 (95% CI:1.089~2.639,P = 0.019),respectively. Conclusion:CKD and albuminuria were common in type 2 diabetes. Strategies to prevent or delay progression of kidney disease in type 2 diabetes,including antidiabetic,antihypertensive and improving anemia,should be carried out early.

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杨 俊,娄青林,顾刘宝,欧阳晓俊,莫永珍,卞茸文.2型糖尿病患者慢性肾脏病相关心血管危险因素分析[J].南京医科大学学报(自然科学版英文版),2012,(12):1731-.

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  • Received:May 13,2012
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  • Online: January 09,2013
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