Objective:To determine the effect of obesity on bone mineral density of lumbar spine and hip in male patients with type 2 diabetes. Methods:The study was carried out in 199 male with type 2 diabetes. Bone mineral density (BMD) at the sites of lumbar spine and hip (lumbar spine L1~L4,femoral neck,Ward’s triangle and total hip) were obtained by dual X-ray absorptiometry. The influence of obesity on BMD was evaluated. Results:According to body mass index,BMDs at lumber spines,total hip,femoral neck and ward’s triangle were significantly higher in obesity subjects compared with non-obese subjects. BMDs at lumber spines and total hip were significantly higher in visceral obesity objects define as waist circumference not less than 90 cm. The significant difference was disappeared in femoral neck and Ward’s triangle. Compared with subjects with normal BMD and osteopenia,those with osteoporosis had lower weight,BMI,waist circumference and hip circumference and were older. BMDs were positively correlated with height,weight,BMI,waist circumference and hip circumference. Only BMDs at hip were negatively correlated with age. After correction of height and weight,BMDs at femoral neck negatively correlated with waist-to-height ratio (r = -0.179,P = 0.019) and hip circumference (r = -0.179,P = 0.019). BMDs at ward’s triangle negatively correlated with waist (r = -0.177,P = 0.019), hip circumference (r = -0.227,P = 0.002) and waist-to-height ratio (r = -0.229,P = 0.002). Conclusion:Visceral obesity in male type 2 diabetes patients is related to lower BMDs at hip and the risk of osteoporosis.