Objective:To analyze the correlation of ILI and positive rate of nucleic acid based on data of influenza surveillance in Jiangsu Province. Methods:The ILI number and positive rate of nucleic acid detection among age groups of three years in Jiangsu Province were caculated and the correlation of ILI and the positive rate was analyzed. Results:From 2011 to the 30th week of 2013,there were differences between ILI and positive rate of nucleic acid detection among age groups.The correlation of ILI and the positive rate of nucleic acid detection was not statistically significant between age of 0~4 years and 5~14 years,although it was significantly different among age groups >14 years. Conclusion:We can achieve more scientific and effective influenza surveillance by improving the quality of ILI reporting and specimen collection and adjustment the monitoring program.