Objective:To observe influence of dopamine on hepatic vein hemodynamics during cardiopulmonary bypass. Methods:Tweenty patients undergoing CABG were randomly divided into dopamine group and control group. The hemodynamics changes (HR,MAP,CVP,CI,et al) and the related hepatic vein flow indicators(hepatic vein diameter,hepatic vein flow,et al) were measured by Transesophageal echocardiography. These data were recorded after general induction,5 minutes after cardiopulmonary bypass beginning,30 minutes after cardiopulmonary bypass beginning,and 30 minutes after off-pump,and the liver and kidney changes were compared between preoperation and postoperation. Results:Blood pressure decreased in the two groups after cardiopulmonary bypass,heart rate of dopamine group was higher than that of the control group after offpump(P < 0.05). The liver blood flow of dopamine group during cardiopulmonary bypass increased compared with preoperation(P < 0.05),but these was no significant difference compared with control group. Creatinine and blood urea nitrogen of dopamine group was lower after surgery compared with control group(P < 0.05). Conclusion:Continous infusion of dopamine with 2 μg/kg-min could increase hepatic blood flow,but it needs further reaearches of appropriate dose of dopamine to getting a better clinical effect.