Abstract:Objective:To investigate factors associated with late-onset fetal growth restriction (FGR) and their impacts on perinatal outcomes. Methods:Maternal and neonatal data from 140 cases of late-onset FGR were collected from Nanjing Maternity and Child Health Care Hospital affiliated to Nanjing Medical University from May 2012 to October 2013. All cases were divided into several groups according to pregnancy complications,gestational weeks (32 to 33+6 weeks for group Ⅰ,34 to 36+6 weeks for group II,37 to 40+4 weeks for group Ⅲ) and delivery modes. Neonatal physical development and morbidities of common diseases were compared among groups. Results:The birth weight and body length of newborns of the group with pregnancy complications were significantly lower than those without pregnancy complications. The morbidities of neonatal septicemia,neonatal pneumonia and acute respiratory distress syndrome (ARDS) of the group with pregnancy complications were significantly higher than those without pregnancy complications. The regression coefficient between neonatal physical development indexes and total gestational weeks was all less than group Ⅱ,and there were no regression relation between neonatal physical development indexes and groupⅠand Ⅲ. The morbidities of neonatal septicemia,neonatal pneumonia and ARDS of groupⅠandⅡwere significantly higher than those of group Ⅲ. The birth weight and body length of term newborns of the cesarean group were significantly lower than those of the vaginal delivery group. No other significant differences were observed between the two groups. Conclusion:The late-onset FGR fetuses display rapid growth and development in pregnancy 34 to 36+6 weeks and the common diseases morbidities of term newborns are relatively low. Therefore,gestational weeks could be extended to 37 weeks if only intensive therapy and close monitoring are available. The perinatal outcomes of late-onset FGR were relatively good;therefore,vaginal delivery with intensive care could be recommended.