Comparison of five creatinine-based glomerular filtration rate estimating equations on renal function evaluation in Chinese living related donor renal transplant recipients
Objective:The aim of this study was to evaluate 5 creatine (Scr)-based glomerular filtration rate (GFR)estimating equations on renal function evaluation in Chinese living related donor transplantation recipients. Methods:We compared 5 Scr-based GFR estimating equations using GFR measurement of 99m Tc-DTPA as the reference test in 39 stable renal transplantation populations from living related donor in our hospital. Bias,precision,accuracy within 30% and 50% ranges from the reference method and agreements of each test were compared. Results:The Scr-based Japanese Society of Nephrology-Chronic Kidney Disease Initiatives (JSN-CKDI) equation had the highest accuracy (71.8% within 30% of the reference)with a bias of only -0.7 ml/(min-1.73m2)and a precision of 12.0 ml/(min-1.73m2). Conclusion:Scr-based JSN-CKDI equation may be the best choice for assessing and monitoring GFR of long-term postoperative Chinese renal transplant recipients.