Objective:To investigate the situation of injury comprehensive surveillance system,find and solve the problem,provide the information base for the work of injury prevention and control. Methods:The data from 2011 to 2012 was used to analyze epidemic situation of injury,characteristics of the hospitalization expense and injury composition,and describe the surveillance work and existing problems. Results:The analysis of injury mortality showed that the resident population number of two surveillance areas was 1 971 633 in 2011 year,the injury mortality was 50.46∕100 000,and 1 985 232 in 2012 year,the injury mortality was 51.28/100 000;The male injury mortality was higher than women in both two surveillance areas from 2011 to 2012;The total Hospitalization expense of two surveillance areas was 208 million,the average expense was 10 751.02 yuan. Hospitalization expense caused by Accidental falls was the highest both in two surveillance areas,the second was Road Accidents,and the expenses were 19 803.42 yuan and 17 061.04 yuan in Pukou district,1 3387.77 yuan and 12 728.26 yuan in Zhangjiagang city;The comparisons of basic characteristics were all statistically significant in two surveillance areas. The top two reasons of Death,Hospitalization,Outpatient and emergency were still Road Accidents and Accidental falls. Conclusion: The hospitalization expense caused by Road Accidents and Accidental falls were the main injury causes,and were also the main reason leading to death,hospitalization,outpatient and emergency,so we should strengthen the integrated control of the two injures,reduce losses caused by the injuregs. There were some problems in the injury comprehensive surveillance system with low information utilization,and we should improve the quality of surveillance data.