Objective:Use color doppler ultrasonography to detect the blood flow alterations of renal artery in hypertensive disorders complicating pregnancy women for the purpose of early diagnosis of renal impairment. Methods:The research included 156 pregnant women chosen in Maternal-Child Health Centers affiliated to Nanjing Medical University. These women were classified into five groups:preeclampsia(PE,n=40),chronic hypertension complicating preeclampsia(CHCPE,n=25),chronic hypertension complicating pregnancy(CHCP,n=21),gestational hypertension(GH,n=22),normal pregnancy(NP,n=48). In 32 to 36 gestational weeks,each woman’s blood serum creatinine(Scr),urea nitrogen(BUN),uric acid(UA),glomerular filtration rate(GFR)were tested and compared. At the same time,we use color doppler ultrasonography to detect the blood flow alterations of renal artery in these women. Results:①In the PE and CHCPE group,the BUN and UA of the participants were significantly higher than that of the NP and CHCP groups. Compared with CHCP,GH and NP groups,the Scr of the participants in PE groups were significantly increased,while the GFR was markedly decreased(P < 0.05). ②The acceleration times of main renal artery(MRA)and segmental artery(SRA)in PE,CHCPE and CHCP groups was remarkably higher than that in NP group(P < 0.05). The acceleration times of SRA in GH group was significantly higher than that in NP group,while there was no difference of AT in MRA between the two groups. Also no difference of peak systolic velocity(Vs),end diastolic velocity (Vd)and resistance index(RI)in MRA and SRA was found among the five groups(P > 0.05). Conclusion:Renal impairment caused by preeclampsia was more quick and severe than that caused by chronic hypertension. AT of renal artery,checked by color doppler ultrasonography,was a sensitive indicator to detect renal impairment early. Using AT,combined with UA and GFR can provide a reliable basis for evaluation of renal function and formulation of treatment plan.