Abstract:Objective:To summarize the predicting role of increased miR-210 expression for survival in patients with breast cancer. Methods:All of relevant studies were identified by searching PubMed,EMBASE,Web of Science and CNKI. Pooled hazard ratios(HRs)with 95% confidence intervals(CIs) for overall survival(OS),recurrence-free survival(RFS),and disease-free survival(DFS)were calculated by Stata 12.0 software. Results:A total of 585 cases from 6 eligible studies were involved for this global meta-analysis. For OS,the pooled HR of higher miR-210 expression in breast cancer was 2.29(95%CI:0.89~5.91,P= 0.086). And for DFS/RFS,the pooled HR of higher miR-210 expression in breast cancer was 2.81(95%CI:1.35~5.87,P=0.006). Conclusion:This meta-analysis suggests that high expression of miR-210 may predict poor survival in patients with breast cancer.