Abstract:Objective:Heart failure, as one of the major reason for cardiovascular death, has emerged as a new challenge for the burden of global cardiovascular disease. Medication therapy can relief symptoms and reduce mortality of heart failure patients. Recently, device-based therapy has been validated by large sample size of clinical trials to be effective treatment by reducing mortalities, reversing ventricular remodeling, and improving life quality of patients with severe heart failure. The present review discussed current device-based therapies for chronic heart failure including cardiac resynchronization therapy, implantable cardioverter defibrillator, cardiac contractility modulation, percutaneous ventricular restoration, vagus nerve and spinal cord stimulation.