Objective:To investigate the value of lung ultrasonic score(LUS)for quantitative ultrasound diagnosis in neonatal in the neonates with acute respiratory distress syndrome(ARDS). Methods:Retrospectively,these participants with the suspected ARDS were considered candidates for the prospective trial between January 2012 and January 2016 in the First Affiliated Hospital of Nanjing Medical University neonatal intensive care unit,and 90 cases were included according to the diagnostic criteria of ARDS in 2012 Berlin. Lung ultrasound examination and lung functions were monitored for evaluation of the neonates with ARDS. Results:The LUS of term ARDS group and premature ARDS group was(15.6~3.9)and(20.5~4.2),respectively,with statistically significant difference (P < 0.05). Conclusion:Bedside lung ultrasound has a better accuracy in diagnosis of neonatal ARDS,which deserves to be popularized in the clinical practice.