Objective: This study is aimed to explore the relationship between thyroid hormone and body composition in the elderly with euthyroid gland. Methods: Seventy-four euthyroid subjects with an average age 74.6±7.7 years old have been involved. Body weight, thyroid function and body composition have been measured. Results: Appendicular muscle mass (ASM) was positively associated with FT3(P=0.003). There is still a positive correlation between the two indexes after adjusting for age, sex and body mass index(BMI) (P=0.011). FT3 was positively correlated with lean subtotal(P=0.024). We found the same correlation between ASW and FT3 in female(P=0.043), but not male, after adjusting for age, sex and BMI.TSH was negatively correlated with appendicular fat mass and fat subtotal(P=0.039; P=0.038).None correlation between the two has been found after adjusting for confounding factors. Conclusion:Thyroid hormone is related with body composition in the elderly with euthyroid gland.