Objective：To analyze the level of circulating endothelial progenitor cells（cEPCs）in patients with stable chronic obstructive pulmonary disease（COPD）. Methods：Major online database including Pubmed，Embase，Web of science were searched to find published case-control studies on the association between cEPCs and patients with stable COPD. The results were analyzed using Stata14 software. Results：A total of 12 studies containing 550 subjects were enrolled. Meta analysis showed that the level of cEPCs was significantly declined in patients with stable COPD（standardized mean difference（SMD）= -1.38，95% confidence interval（CI）（-2.01，-0.74），Z=4.23（P < 0.001）. Subgroup analysis indicated that using flow cytometry the level of cEPCs was remarkable decresed in patients with stable COPD than normal controls；however，there is no statistic significance in the level of cEPCs between patients with stable COPD and controls by counting EPCs colony forming units. By sensitivity analysis，funnel plot，and “trim and fill”，it showed that the results were robust. Conclusion：The level of cEPCs is low in patients with stable COPD compared with healthy controls，especially by the method of flow cytometry，which may lead to the deficient capacity of endothelial repairing.