Risk factors on the short⁃term outcome of DCD kidney transplanted recipients:A single⁃center study
CSTR:
Author:
Affiliation:

Clc Number:

Fund Project:

  • Article
  • |
  • Figures
  • |
  • Metrics
  • |
  • Reference
  • |
  • Related
  • |
  • Cited by
  • |
  • Materials
  • |
  • Comments
    Abstract:

    Objective:To discuss donors’ and recipients’ risk factors for the short-term outcomes of kidney transplanted recipients from donation after citizen’s deceased(DCD). Methods:We retrospectively analyzed the information of donors and recipients at the Kidney Transplantation Center,Jiangsu Province Hospital from January 1,2015 to Oct 31,2016. We compared the risk factors of delayed graft function(DGF)and 1-year estimated-glomerular filtration rate(eGFR)of recipients. Results:The DGF rate of kidney transplanted recipients from DCD was 28.2%. On univariate analysis of DGF,female in donor(P=0.019),body mass index(BMI)of donor(P=0.027),warm ischemia time(WIT,P=0.044),and the history of cardio-pulmonary resuscitation(CPR,P=0.042)were showed significant differences. On multivariate analysis,age of donor(P=0.027)and WIT(P=0.042)were independent risk factors for the incidence of DGF. Recipients with DGF had more hospital stay(P=0.020),more hospitalization expenses(P=0.012)and more incidence of acute rejection(AR,P<0.001),compared with recipients without DGF. On multivariate analysis of 1-year eGFR of recipients,age of donor(P=0.005)and the complications of AR(P=0.034)were independent risk predictors. Conclusion:Age of donor and WIT were independent risk factors for the incidence of DGF of recipients. Age of donor and the complications of AR were independent risk predictors for 1-year eGFR of recipients. These factors should be considered while evaluating potential donors.

    Reference
    Related
    Cited by
Get Citation

阙宏亮,韩志坚,耿 亮,居小兵,陶 俊,陈 浩,孙 黎,谭若芸,顾 民.器官捐献肾移植受者近期预后的影响因素分析[J].南京医科大学学报(自然科学版英文版),2018,(5):616-621,627.

Copy
Share
Article Metrics
  • Abstract:
  • PDF:
  • HTML:
  • Cited by:
History
  • Received:January 04,2018
  • Revised:
  • Adopted:
  • Online: May 16,2018
  • Published:
Article QR Code