Risk factors on the short⁃term outcome of DCD kidney transplanted recipients:A single⁃center study
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    Abstract:

    Objective:To discuss donors’ and recipients’ risk factors for the short-term outcomes of kidney transplanted recipients from donation after citizen’s deceased(DCD). Methods:We retrospectively analyzed the information of donors and recipients at the Kidney Transplantation Center,Jiangsu Province Hospital from January 1,2015 to Oct 31,2016. We compared the risk factors of delayed graft function(DGF)and 1-year estimated-glomerular filtration rate(eGFR)of recipients. Results:The DGF rate of kidney transplanted recipients from DCD was 28.2%. On univariate analysis of DGF,female in donor(P=0.019),body mass index(BMI)of donor(P=0.027),warm ischemia time(WIT,P=0.044),and the history of cardio-pulmonary resuscitation(CPR,P=0.042)were showed significant differences. On multivariate analysis,age of donor(P=0.027)and WIT(P=0.042)were independent risk factors for the incidence of DGF. Recipients with DGF had more hospital stay(P=0.020),more hospitalization expenses(P=0.012)and more incidence of acute rejection(AR,P<0.001),compared with recipients without DGF. On multivariate analysis of 1-year eGFR of recipients,age of donor(P=0.005)and the complications of AR(P=0.034)were independent risk predictors. Conclusion:Age of donor and WIT were independent risk factors for the incidence of DGF of recipients. Age of donor and the complications of AR were independent risk predictors for 1-year eGFR of recipients. These factors should be considered while evaluating potential donors.

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Que Hongliang, Han Zhijian, Geng Liang, Ju Xiaobing, Tao Jun, Chen Hao, Sun li, Tan Ruoyun, Gu Min. Risk factors on the short⁃term outcome of DCD kidney transplanted recipients:A single⁃center study[J].,2018,(5):616-621,627.

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History
  • Received:January 04,2018
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  • Online: May 16,2018
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