Objective：By comparing with the friction and wear properties of three grown materials and tooth enamel in vitro experiment，to provide a certain experiment basis for choosing the repair materials with the wear resistance close to nature tooth in clinical. Methods：Choosing the veneering porcelain with highly polishing，aierchuang zirconia and machinable compound resin material Lava Ultimate as the experiment group，the tooth enamel was chosen for the control group. Taking the steatite ceramics as resist ware material，simulating the oral environment to do the friction and wear experiment of the two material on the CFT-Ⅰ type material surface properties general-purpose tester. By testing the inspection of surface roughness Ra，surface hardness，abrasion loss and rubbed surface to research the friction and wear properties between abrasion loss and different materials. The statistical analysis was conducted by the method of one-way analysis of variance. Results：Compared with the enamel group，the self-abrasion loss of the three materials and abrasion loss of the resist ware material have statistic difference（P < 0.05），in which the abrasion loss between Lava Ultimate and resist ware material closed to the abrasion loss between tooth enamel and resist ware material most. Conclusion：Compared with veneering porcelain，the zirconia had a better abrasive resistance and lower abrasion of resist ware material. Compared with tooth enamel，the Lava Ultimate had a better abrasive resistance and lower abrasion of resist ware material. Compared with the veneering porcelain and zirconia，Lava Ultimate closed to the tooth enamel more on the aspects of wear-resisting property and abrasion of resist wear material .