Objective：To compare the visual acuity，contrast sensitivity and visual quality of patients with high myopia after the implantation of AT LISA tri 839 MP multifocal intraocular lens and CT SPHERIS 209M monofocal intraocular 1ens. Methods：Forty-four patients（44 eyes）were involved and divided into two groups in this study. The trail group（22 patients，22 eyes）received AT LISA tri 839MP multifocal intraocular lens implantation and the control group（22 patients，22 eyes）received CT SPHERIS 209M monofocal intraocular lens implantation after phacoemulsification. Parameters including visual acuity，contrast sensitivity at different spatial frequencies（3，6，12，18 cpd）in bright and dark circumstances，independent spectacles ratio，satisfaction and photic phenomena were observed. The post-operative visual acuity included the information of uncorrected distance visual acuity（UCDVA），uncorrected intermediate visual acuity（UCIVA），uncorrected near visual acuity（UCNVA），best corrected distance visual acuity（BCDVA），distance corrected intermediate visual acuity（DCIVA），and distance corrected near visual acuity（DCNVA）. The SPSS 16.0 statistic software was used to analyze the data. Results：The UCIVA，UCNVA，DCIVA，DCNVA，independent spectacles ratio and satisfaction of the trail group were better than those of the control group（all P < 0.05）. The mean contrast sensitivity at spatial frequency of 18 cpd in bright and dark circumstances of the control group was higher than that of the control group（P < 0.05）. The incidence of glare and halo showed no significantly statistical difference between two groups（P=0.50）. Conclusion：AT LISA tri 839MP multifocal intraocular lens provided better intermediate and near vision，higher independent spectacles ratio and more satisfaction of patients than CT SPHERIS 209M monofocal intraocular lens.