Objective：Porcine naive-like embryonic stem cells were induced to differentiate into neural cells in vitro，which provided basic information for the repair and treatment of the neurological disease. Methods：The neural-inducing culture medium with small molecule compounds β-mercaptoethanol，B-27 and heparin was used to differentiate the porcine naive-like embryonic stem cells towards the neural-like cells. We have derived neural-like cells with identification of the neural specific gene expression. We detected whether these cells could show limited pluripotency. Results：The neural-like cells had obvious neuronal cell structure. RT-PCR and immunofluorescence data showed that the differentiated neurons expressed a variety of neural cell-specific genes. QPCR results showed that the expression of pluripotent factors was decreased significantly after differentiation process and the expression of nerve-specific genes was significantly increased. The results of immunofluorescence showed that the rate of light neurofilament protein（NF-L）positive cells reached 79%. Conclusion：Neural cells could be directly induced from porcine naive-like embryonic stem cells in vitro.