Analysis of risk factors for extrauterine growth retardation in mid⁃late preterm infants discharged from hospital
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    Abstract:

    Objective:This study aims to analyze the incidence of extrauterine growth retardation(EUGR) and related risk factors of late-term premature infants discharged from hospital,so as to provide reference for prevention and treatment of EUGR in the future. Methods:The clinical data of 1 374 mid-late preterm infants enrolled in the NICU from January 2016 to June 1818 in Hainan Maternal and Children’s Medical Center were collected. Infants were divided into EUGR group and non-EUGR group according to the body weight at discharge,and indexes of EUGR group and non-EUGR group were compared. All data were statistically analyzed using SPSS22.0 software. Results:The incidence of EUGR was 26.74% in mid-term preterm infants and 26.14% in late preterm infants. There was no significant difference in the incidence of EUGR between mid-term preterm infants and late preterm infants (χ2 =0.033,P=0.855).The lower the birth weight was,the higher the incidence of EUGR was. The differences in the incidence of EUGR in preterm infants with different birth weights were statistically significant(χ2 =81.746,P < 0.001);incidences of brain injury,sepsis and retinopathy of prematurity in the EUGR group were higher than those in the non-EUGR group(P < 0.05);total enteral nutrition time,oxygen inhalation time,fasting time and hospitalization time were longer in EUGR group than in non-EUGR group(P < 0.001). Incidences of gestational hypertension,multiple births,IUGR(intrauterine growth retardation) and umbilical cord abnormalities were higher in EUGR group than in non-EUGR group(P < 0.05). The fetal weight of EUGR group was significantly lower than that of non-EUGR group(P < 0.05);Logistic regression analysis showed that multiple births,IUGR,umbilical cord abnormalities,birth weight and hospital-stay time were independent risk factors for EUGR. Conclusion:The occurrence of EUGR in mid-late preterm infants is related to multiple births,IUGR,abnormal umbilical cord,low birth weight and long hospital stay. Strengthening perinatal health care,preventing the birth of low-weight infants,reasonable nutritional support,actively preventing high-risk factors and reducing various complications after birth are important measures to reduce the occurrence of EUGR in mid-late preterm infants.

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曹 祥,韦 伟,黄晓燕,羊 玲.中晚期早产儿出院时宫外生长发育迟缓危险因素的分析[J].南京医科大学学报(自然科学版英文版),2019,(9):1345-1349.

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History
  • Received:December 11,2018
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  • Online: September 29,2019
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