Objective：This study aims to analyze the incidence of extrauterine growth retardation（EUGR） and related risk factors of late-term premature infants discharged from hospital，so as to provide reference for prevention and treatment of EUGR in the future. Methods：The clinical data of 1 374 mid-late preterm infants enrolled in the NICU from January 2016 to June 1818 in Hainan Maternal and Children’s Medical Center were collected. Infants were divided into EUGR group and non-EUGR group according to the body weight at discharge，and indexes of EUGR group and non-EUGR group were compared. All data were statistically analyzed using SPSS22.0 software. Results：The incidence of EUGR was 26.74% in mid-term preterm infants and 26.14% in late preterm infants. There was no significant difference in the incidence of EUGR between mid-term preterm infants and late preterm infants （χ2 =0.033，P=0.855）.The lower the birth weight was，the higher the incidence of EUGR was. The differences in the incidence of EUGR in preterm infants with different birth weights were statistically significant（χ2 =81.746，P < 0.001）；incidences of brain injury，sepsis and retinopathy of prematurity in the EUGR group were higher than those in the non-EUGR group（P < 0.05）；total enteral nutrition time，oxygen inhalation time，fasting time and hospitalization time were longer in EUGR group than in non-EUGR group（P < 0.001）. Incidences of gestational hypertension，multiple births，IUGR（intrauterine growth retardation） and umbilical cord abnormalities were higher in EUGR group than in non-EUGR group（P < 0.05）. The fetal weight of EUGR group was significantly lower than that of non-EUGR group（P < 0.05）；Logistic regression analysis showed that multiple births，IUGR，umbilical cord abnormalities，birth weight and hospital-stay time were independent risk factors for EUGR. Conclusion：The occurrence of EUGR in mid-late preterm infants is related to multiple births，IUGR，abnormal umbilical cord，low birth weight and long hospital stay. Strengthening perinatal health care，preventing the birth of low-weight infants，reasonable nutritional support，actively preventing high-risk factors and reducing various complications after birth are important measures to reduce the occurrence of EUGR in mid-late preterm infants.