The novel coronavirus pneumonia，which spread rapidly across China and other countries，has been proved the obviou sinfectivity and harm to human health. Since there is no specific antibody against the novel coronavirus in the body，it is highly spread after human infection，which threat to human health and public health security in the world. At present，there is no available vaccine and specific antiviral drugs for the novel coronavirus pneumonitis，so the antibody development mediated prevention and clinical treatment is particularly important. This review evaluates the research on antibody detection，neutralization antibody and subunit vaccine to the novel coronavirus pneumonia，which aimed to focus on the antibody strategies against the novel coronavirus，providing new ideas for the prevention and control of the novel coronavirus pneumonia.