Vitamin D plays an important role in calcium absorption and bone metabolism. More and more studies have found that vitamin D is also involved in the modulation of infection,inflammatory and immune responses.Vitamin D also plays an important role in regulating a variety of cells. Vitamin D insufficiency and deficiency are common worldwide,which is more common in children with bronchial asthma. The pathophysiology of bronchial asthma is chronic inflammation,airway hyperresponsiveness and airway remodeling. Vitamin D may affect the occurrence and development process of asthma. This review summarized the correlation between vitamin D and the morbidity of asthma,the mechanisms of vitamin D affecting asthma,and the clinical effects of vitamin D as an adjuvant therapy for childhood asthma.
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CHEN Xue, CHEN Meng. Vitamin D and childhood asthma[J].,2020,(3):454-460.