Objective：To investigate the characteristics of 24-hour urinary electrolyte excretion in non-dialysis patients with chronic kidney disease（CKD）and its correlation with clinical parameters. Methods：A total of 752 patients with CKD from May 2017 to April 2019 were selected to retrospectively analyze the relationship between 24-hour urinary electrolytes and clinical indicators. Results：Our results showed that there was no significant difference in urinary sodium or urinary potassium excretion in patients with different stages of CKD1-4. However，urinary calcium and urinary phosphorus excretion decreased with the decline of glomerular filtration rate. Besides，24-hour urinary sodium and urinary potassium were positively correlated with 24-hour urine protein，regardless of the complication of high blood pressure or diabetes. Meanwhile，24-hour urinary calcium was negatively correlated with 24-hour urine protein and 24-hour urinary phosphorus was showed no correlation with 24-hour urine protein. The prevalence of hypertension and cardiovascular disease in the low urine phosphorus group was higher than that in the high urine phosphorus group，the prevalence of cardiovascular disease in the low urine calcium group was higher than that in the high urine calcium group，and the prevalence of diabetes in the high urine potassium group was higher than that in the low urine potassium group. Conclusion：The level of urine electrolyte in patients with CKD is associated with urine protein，the prevalence of hypertension，diabetes and cardiovascular diseases. Its management deserves more attention.