Objective：This study aims to investigate the relationship between metabolic syndrome，its components and Fuhrman grade，TNM stage in clear cell renal cell carcinoma patients. Methods：From January 2018 to December 2019，clinical data of 153 cases in our department was analyzed retrospectively，including age，gender，smoking，drinking，body mass index，hypertension，hyperglycemia，hyperlipidemia，tumor diameter，Fuhrman grade and TNM stage. The pathological grading system used was Fuhrman grading system with grade Ⅰ and Ⅱ accepted as high differentiation，grade Ⅲ and Ⅳ as poor differentiation. In addition，the TNM classification of 2010 was used，with T1a and T1b recognized as low stage，T2a and T2b as high stage. The differences of measurement data were compared through t tests，while the differences of count data was analyzed by Chi-square tests. Moreover，logistic regression analysis was used to find independent risk factors. Results：Metabolic syndrome was significantly associated with histological grade and stage（P < 0.05）. Hypertension，hyperglycemia and hyperlipidemia were also related to histological grade and stage（P < 0.05）. Multivariate Logistc regression analysis also showed that hypertension，hyperglycemia and hyperlipidemia were associated with tumor pathological grade（P < 0.05），while hyperglycemia and hyperlipidemia were associated with tumor stage（P < 0.05）. Conclusion：Patients with metabolic syndrome were found to have significant higher grade and T stage of clear cell renal carcinoma.