Objective：To investigate the maturity，vascularization and nonrenal differentiation of kidney organoids using induced renal organoids derived human pluripotent stem cells（hPSCs）. Methods：hPSCs were induced into renal organoids cells through a renal epithelial cell differentiation kit. The renal organoids structures were highly expressed with specific kidney markers CDH1，LTL，and PODXl by immunofluorescence method. The microstructures of glomeruli and tubules were observed by transmission electron microscopy；The animals were sacrificed under the renal capsule of SCID mice for 4 weeks，the grafts were taken for histomorphological observation，and the expressions of HNA，CDH1，PODX and MECA-32 were observed by immunofluorescence method. Results：The kidney markers CDH1，LTL，and PODX were positively expressed. Immature podocytes and tubular structures were observed by transmission electron microscopy. The kidney organoid volume increased after transplantation，blood vessels were visible to the naked eye，and HE stained grafts were visible red blood cells and cartilage-like tissues，HNA，CDH1，PODX and MECA-32 were positively expressed. Conclusion：hPSC can induce immature kidney organoids structures in vitro. In vivo，renal orgaoids structures can complete vascularization and continue to grow，but there were a large number of non-renal structures.