The immune system has an important impact on the occurrence，development and prognosis of tumors. With the progress of research，the immunotherapy of tumors has made great progress. Current immunotherapy mainly includes immunological checkpoint blockade，non-specific activation of the immune system，adoptive cellular immunotherapy，tumor vaccine，etc. Among them，programmed death 1（PD-1） and its ligand （PD-L1） signaling pathway and cytotoxic T-lymphocyte antigen 4 （CTLA-4） are the research hotspots of clinical treatment of advanced tumors. This article aims to review the application of immunosuppressive drugs in urinary tumors.