Objective:To evaluate the effect of a new collagen-type artificial bone graft on the repair of alveolar bone defect after single tooth extraction. Methods:A total of 89 patients with a single molar planned to be extracted at our institution were included and randomly divided into two groups. The experimental group was implanted with the new collagen-type bone graft while the control group was implanted with Bio-Oss collagen immediately after tooth extraction. After then,all wounds were coated by the absorbable biological membrane. The height,width and density of alveolar bone were tested by CBCT immediately and 6 months after surgery,and clinical examinations were conducted three times during the period. Results:There was no significant difference in the change of alveolar bone height and width between the experimental group and the control group(P > 0.05). In the experimental group,the lingual bone height decreased by(0.75 ± 0.95)mm,while no significant change was found in the buccal bone height and the width. In the control group,the height decreased by(0.54 ± 1.47)mm in the buccal and decreased by(1.20 ± 1.18)mm in the lingual,whereas bone width did not change significantly. Bone density of the experimental group was higher than that of the control group immediately after surgery(P < 0.01),but no significant differences were found between the two groups 6 months after surgery(P > 0.05). Clinical examination showed that there was no significant difference in wound healing score between the two groups. Conclusion:The new collagen-type artificial bone graft has similar effects to Bio-Oss collagen on the repair of alveolar bone defect after extraction,and is slightly better in preservation of the buccal bone.