Objective:To assess the exam paper,evaluate the teaching results and improve the test bank construction. Methods:Final examination papers of pathology,pharmacology,obstetrics and gynecology,internal medicine for five-year medical students from 2003 to 2005 Grade in Nanjing medical university were analyzed by applying education measurement. Results:Reliability coefficient of the four courses was above 0.6,and moreover 91.7% was above 0.7,but the difficulty and discrimination coefficient were not satisfied. Conclusion:Both the preclinical and clinical courses examination papers have some defects without the instruction of education measurement,for example,the reliability can be evaluated,and the difficulty and discrimination coefficient of some items are not conform to the principle of the test,so some improvements should be recommended and performed.