Objective:To investigate the correlation between obstetrical complications and depressive disorder. Methods:Depressive disorder probands and their adult sibling were diagnosed using CCMD-3 criteria. Obstetrical data from maternal reports were scored, applying published scales that take into account number and severity of complication. Results:The scores of obstetric complication and prenatal complications and low birth weight were significantly worse in probands than siblings without depressive disorders. Conclusion:Results suggest obstetric complications are etiologically significant in depressive disorder.