Patients’ health preferences are important for improving service quality and patients’ satisfaction. The aim of this study was to quantitatively measure patient preference for orthodontic treatment options for adolescents and to provide a reference for the accurate provision of orthodontic treatment options. This study was based on the Discrete Choice Experiment(DCE)method,and a total of four attributes (orthodontic aesthetics,orthodontic comfort,treatment cost,and follow ? up interval)were included through literature review and expert consultation. A D?efficiency design was used to create a choice set with the aid of the software Ngene 1.2,and a questionnaire survey was conducted with parents/guardians of adolescents aged 12~17 years in a tertiary dental specialist hospital in Anhui Province. A conditional Logit regression model was used for preference analysis. DCE results showed that,except for the follow?up interval,the other three research attributes significantly influenced orthodontic treatment options. Treatment cost was the most important attribute influencing orthodontic treatment options,followed by orthodontic comfort and aesthetics. Compared with the slightly poor comfort,the patients were willing to pay 21 500 yuan more for the orthotics with very good comfort. The aesthetic level of orthotics was raised from slightly poor to very good,and the probability of scheme selection was expected to increase by 62.43%. This study is the first application of DCE research in the field of oral health in China and provides a reference for the extension of other clinical options decision preferences.