A comprehensive evaluation of the medical service capacity of 33 tertiary comprehensive public hospitals in Anhui Province was conducted by applying entropy TOPSIS，osculating value method，and RSR to explore ways of improving the medical service capacity of tertiary comprehensive public hospitals in Anhui Province，and to provide scientific basis for further reformation of public hospitals. The ranking results obtained by the three evaluation methods are similar，the difference between the three levels of“good”“medium”and “poor”obtained from the graded results of the RSR method is statistically significant，and there is a large gap between hospitals of different levels. Most of the tertiary comprehensive public hospitals in Anhui Province are at an average level of medical service capacity with regional differences between northern Anhui，central Anhui， and southern Anhui. Further improvements should be made to the process of consultation services，reasonable control of medical costs，and optimization of healthcare resource allocation.