The integration of medication and prevention aims to break the gap between public health and the healthcare service system，establishing a comprehensive and three - dimensional healthcare service system through the integration and sharing of prevention and healthcare resources. From the perspective of historical evolution，the integration of medication and prevention has evolved from the dominance of public logic in the planned economy era to the gradual penetration of market mechanisms after reform and opening up and then to the new wave of healthcare reform that balances public responsibility and market dynamic. From the realistic narrative，the integration of medication and prevention can be divided into four types：medical medication - prevention stagnation，medication over prevention，prevention over medication and medical prevention and treatment integration，according to the dual attributes of public and market. Each type reflects different aspects and challenges in current practice. To address these challenges，the study proposes strategies from three dimensions： value reconstruction， governance transformation， and model transformation to promote the continuous optimization and innovation of the ecology of medication and prevention integration and rely on the dual enabling mode of“system -technology”to accelerate the efficiency and service quality of medication and prevention integration，therefore establishing a highly efficient and collaborative healthcare management that covers the entire life cycle.