Abstract： [Objective]To analysis of content of inspection and quarantine departments need to focus on the entry-exit of viral safety of biological products management and to propose countermeasures. [Method] By analyzing the urgency of control the biological products viral safety and domestic and international biological products viral safety management status, it explores the focus on the entry-exit of biological products virus safety management of the inspection and quarantine departments. [Conclusion] The entry-exit Biological Products virus security management of inspection and quarantine department of need to focus on the virus safety of the source material of the entry-exit of biological products, tracking observation ,the entry-exit of Biological Products viral safety , to carry out Category management of unit using entry and exit biological products , strengthening cooperation and enhancing the capacity of inspection and quarantine departments to monitor entry-exit biological products virus safety. Key words : entry-exit biological products; viral safety management