The medical dissension and violence has been happened frequently in recent years, the relationship between doctor and patient have been become a focus of public concern. The doctor-patient relationship affected by numerous factors, patients ' Interest claim is key factor influencing the doctor-patient relationship, other factors affect indirectly the doctor-patient relationship through the interest claims. Interest claims can be attributed to four categories: health demands, economic demands, psychological demands and service demands, these demands are governed by social factors, medical factors and patient factors. The interest gap led to resentment and hostility, and raise contradictions and disputes between doctors and patients, and even incidents of violence against medical staff.