China, as one of the initiative countries to found World Health Organiazation (hereafter referred to WHO), shares a series of categories of cooperation mode with WHO. The contents of cooperation have been more and more enriched, and the priorities have been more and more expanded. The approach to cooperation has developed from being passive assisted to active giving assistance and guidance. To generates the historical cooperation and influence factors of China China-WHO cooperation strategy will somehow provide constructive background information for exerting China’s international influence and promoting global health according to the trendency of global health, actual needs of health care in China and WHO’s positions and advantages.