Abstract Objective: By investigating the influencing factors on the quality of the college students' mental health education curriculum teaching, offer advice for college students' mental health education curriculum reform. Methods: Randomly selected to participate in the \"college students' mental health education in JiangSu province\" A good lesson \"exchange of recognition\" of 150 teachers and three part of colleges and universities take over the course of 400 students in colleges and universities as the research sample, according to the questionnaire of teachers, students, respectively, for teachers and students in sampling survey. Results: (1) The teachers think that restricting factors on the quality of the college students' mental health education curriculum, the first of the list is the school management factors. Different types of school teachers for the factors influencing the teaching quality of "students do not take this factor" statistical differences ( χ2= 8.243, P < 0.05). (2) The students think the influencing factors on the quality of the college students' mental health education curriculum at first is teacher. Students of different schools of teaching quality factors to influence factors "charisma of teachers" statistical differences (χ2 = 22.078, P < 0.001). Conclusion: The quality of teachers, teaching management, students' attitude toward this course are the important factors that affect teaching quality of college students' mental health education.