The practice of the theory of international regulation internalization is not only contributing to absorbing and integrating “easy to arouse intensive response in social society” and “highly concerned to public interest” international regulation, concept or promise into the country, but also on some level facilitating country’s promise to international promise, afterwards realizing front-page development of those international regulation, concept or promise at global level. This paper based on the theory of international regulation internalization analyzes the way of international regulation and concept internalizing in China in the field of environmental and health, summarizes the features, therefore based on the current situation of China-WHO communication proposed enlightenment and suggestion on deepening future interactive cooperation and development with WHO.