Objective: To analyze the crime of illegal medical practice trails in Jiangsu in 2015 to find out the causes of crime and the effect of law enforcement and criminal trails to curb the illegal medical practice. Methods: To select and analyze the completed cases of illegal medical practice in each court in Jiangsu. Results: Most of these penalty materials happened in north areas and counties of more outsiders in Jiangsu with low accessibility of medical service; the offenders of 92 cases were punished by administration and then commit a crime again; the adjudication of punishment of part of the judicial apparatus were too lenient to the offenders. Proposals: Solving the problem of the bottom of the public medical treatment to eradicate the living soil of illegal medical practice; strengthening the punishment of administrative law enforcement to combat illegal medical practice to change the status quo of depending on penalty measures too much; standardizing the work of criminal trail to hold the last line of struggling with illegal medical practice.