Objective：To explore the reliability and validity of Connor-Davidson Psychological Resilience Scale (Connor-Davidson Resilience Scale, CD-RISC) in drug abusers on treatment. Methods ：A total of 656 compulsory drug addicts were test with CD-RISC, and the reliability and validity of the measurement results were analyzed. Result ：After exploratory factor analysis, 5 factor models were obtained, including subjectivity, problem processing, stability, tenacity and persistence. The cumulative variance was explained as 56.94%. The Cronbach alpha coefficient of the total scale and each factor was 0.628~0.905; The test-retest reliability coefficient of the total score and each factor was: 0.633~0.853; Confirmatory factor analysis results: c2/DF=1.98, GFI=0.90, AGFI=0.87, NFI=0.84, CFI=0.91, RMSEA=0.06. The fitting results were good and better than the source scale in this population. The correlation between the total score, subjective and tenacity factors and neuroticism factors in the Chinese Big Five Personality Inventory brief version (CBF-PI-B) was statistically significant. Conclusion：The revised Connor-Davidson Resilience Scale with 5 factor model has good psychological measurement indicators in drug abusers on treatment, and applicable to the psychological toughness index of this population.