Abstract ：Objective To investigate the quality of life of hypertension patients in rural areas of Lianyungang, and to explore the influencing factors. Methods By using the method of multi-stage random sampling in the rural community of Lianyungang free medical field sample of 2398 people (over 35 years) in patients with hypertension as the research object, and their quality of life and its influencing factors were investigated by using the SF-12 scale. Results The quality of life of hypertension patients in rural area of Lianyungang was 68.57±24.21, and the normal score was up to 76.5%. The score of mental health was 74.172±2.96, and the normal score was up to 82.7%.The physical scores were influenced by health self-assessment, pain / discomfort, age, duration of illness, gender, and income.he influencing factors of psychological score were self-rated health, pain / discomfort, gender, family history of hypertension and marital status. Conclusion Lianyungang city rural hypertensive patients overall quality of life level is higher, but the long duration of disease of low-income elderly female physical health status is poor, and the mental health status of widowed women with hypertension family history is poor.Therefore, in order to further improve the quality of life of rural hypertensive patients, we should pay attention to humanistic care while strengthening physical health.The focus is on female patients who are in poor health and have pain / discomfort