WeChat has been widely used in college students' life and study. “WeChat-assisted teaching mode” has been developed that draws widespread attention of the education sector both internal and abroad. It realizes the full participation of teaching and learning as well as profound changes brought to educational philosophy and teaching methods. Preventive medical education should actively adapt to the development of higher education law both from internal and abroad, as an opportunity to reform the development of “WeChat-assisted teaching mode”, e.g. the selection of high-quality preventive medical education resources combined with the characteristics of preventive medical education, and the establishment of the model which is needed in preventive medical education teaching. Based on the analysis of function and strength of WeChat, we will discuss the feasibility of the establishment of preventive medical “WeChat-assisted teaching mode”, as well as the idea of introducing WeChat in preventive medical teaching.